One of the most controversial topics in acne treatment is the relationship between vitamin B5 and acne. In 1995, Dr. Lit-Hung Leung did a research that attempted to treat acne patients using vitamin B5. His hypothesis was that if the body lacks pantothenic acid, more androgens would be produced and fatty acids would be released via oil glands, resulting in an outbreak of acne. It was noticed that the patients started to get rid of acne soon and serious cases took up to six months to cure.

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